One-Step Preparation of Green Fabric for Continuous Antibacterial Applications

• 作者: Rongkang Huang Minghui Hu Weiwen Liang Juanjuan Zheng Yang Du Yanhuan Lin Huaiming Wang Wentai Guo Zhantao Zeng Chuangkun Li Ming Li Hui Wang Xingcai Zhang
• 来源期刊: 工程（英文）
• 年，卷（期）: 2021,（3）
• 所属期刊栏目: Green Chemical Engineering—Article
• 页码范围: 326-333
• 页数: 8页
• 语种: 英文

摘要

Polypropylene (PP) scaffolds are the most commonly used biomedical scaffolds despite their disadvan-tages,which include problems with adhesion,infection,and inflammatory responses.Here,we report on the successful development of a facile one-step method to fabricate a series of novel triclosan poly-dopamine polypropylene (TPP) composite scaffolds and thereby effectively improve the biocompatibility and long-term antibacterial properties of PP scaffolds.The antibacterial triclosan can effectively interact with dopamine during biocompatible polydopamine formation on the PP scaffold by one-step green fab-rication.Thanks to the sustained release of triclosan from the biocompatible polydopamine coating,a 5 mm × 5 mm sample of TPP-coated scaffold made with a triclosan concentration of 8 mg.mL-1 (referred to herein as TPP-8) exhibited a continuous antibacterial effect against both Escherichia coli (E.coli) and Staphylococcus aureus (S.aureus) for more than 15 d,at maximum antibacterial volumes of 2 and 5 mL,respectively.Our study establishes a new direction for facile long-term antibacterial studies for medical applications.