SARS-CoV-2 vaccines:anamnestic response in previously infected recipients

• 作者: Jyothi N.Purushotham Neeltje van Doremalen Vincent J.Munster
• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2021,（8）
• 所属期刊栏目: RESEARCH HIGHLIGHTS
• 页码范围: 827-828
• 页数: 2页
• 语种: 英文

摘要

The continued evolution of SARS-CoV-2 has raised questions regarding the ability of prior immunity to early pandemic strains to afford protection against emerging variants.In a recent study,Stamatatos et al.demonstrate that currently approved mRNA vaccines elicit antibodies capable of neu-tralizing heterologous antigen and they further show that single-dose vaccination triggers an anamnestic response in individuals with pre-existing anti-RBD IgG developed through previous SARS-CoV-2 infection.