N6-methyladenine DNA Demethylase ALKBH1 Regulates Mammalian Axon Regeneration

• 作者: Qiao Li Cheng Qian Harry Feng Tyger Lin Qingsan Zhu Ying Huang Feng-Quan Zhou
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（6）
• 所属期刊栏目: Letter to the Editor
• 页码范围: 809-814
• 页数: 6页
• 语种: 英文

摘要

Dear Editor, DNA methylation is a key epigenetic regulatory approach for many biological processes,such as genomic imprinting,epigenetic memory maintenance,aging,and neural devel-opment.In addition to 5-methylcytosine,DNA methylation at N6-deoxyadenosine (N6-mA) is the most prevalent DNA modification in prokaryotes[1].With the advances in various deep sequencing techniques,recent studies have started to find N6-mA in eukaryotes,including humans androdents [2-7].