Distinct phosphoinositides define the biotrophic interface of plant-microbe interactions

• 作者: Li Qin Yangdou Wei
• 来源期刊: 分子植物（英文版）
• 年，卷（期）: 2021,（8）
• 所属期刊栏目: Spotlights
• 页码范围: 1223-1225
• 页数: 3页
• 语种: 英文

摘要

Phosphoinositides,also known as phosphatidylinositol phos-phates(PIPs),are a minor class of anionic phospholipids in cell membranes that have profound importance in a variety of cellular processes,such as cell signaling,membrane trafficking,and cytoskeletal dynamics.Phosphoinositides are the phosphory-lated derivatives of phosphatidylinositol at the 3,4,or 5 positions of the inositol head group,resulting in a total of seven possible phosphoinositide species(Noack and Jaillais,2020).The spatial distribution of these phosphoinositides determines the physical properties of membranes,including surface charge,curvature,and/or clustering of proteins and lipids.By interacting specifically with phosphoinositide-binding proteins,phosphoino-sitides regulate the composition of proteins and lipids of mem-branes and contribute to organelle identity(Noack and Jaillais,2020).In addition,phosphoinositides and their derivatives may act as signaling molecules,as their rapid turnover is regulated by multiple kinases and phosphatases.