Review on the relationship between TLR2/4 and digestive diseases

• 作者: Kai-Wen Lin Tang Deng Hui-Juan Qu Na Wei
• 来源期刊: 海南医科大学学报（英文版）
• 年，卷（期）: 2021,（6）
• 所属期刊栏目: Review and lectures
• 页码范围: 75-78
• 页数: 4页
• 语种: 英文

摘要

Toll-like receptor (TLRs) is one of the important recognition receptors in the innate immune defense system, which plays a key role in mediating inflammatory response and related signal transduction. In the TLRs family, TLR2/4 has been widely studied because of its close relationship with the occurrence and defense of digestive diseases, and studies have shown that the synergism between TLR2/4 is the basis of mediating inflammatory response and immune response. This article summarizes the research on the correlation of TLR2/4 in digestive system diseases, in order to provide ideas for the clinical treatment and research of digestive system diseases.