High mobility group box-1 protein as a therapeutic target in perinatal hypoxic-ischemic brain injury

• 作者: Kazuki Hatayama Barbara S.Stonestreet
• 来源期刊: 中国神经再生研究（英文版）
• 年，卷（期）: 2021,（10）
• 所属期刊栏目: Perspectives
• 页码范围: 2006-2007
• 页数: 2页
• 语种: 英文

摘要

Perinatal hypoxic-ischemic (HI) brain injury is a leading cause of morbidity and long-standing disability in newborns (Millar et al., 2017). Improved neonatal intensive care has increased survival in infants with pregnancy and birth related complications. Nonetheless, many surviving neonates exhibit neurological abnormalities that can persist throughout life (Millar et al., 2017). Early neuroprotective strategies have the potential to improve neurological outcomes and attenuate developmental delay in neonates.