External application of a Nocardia rubra cell wall skeleton in the treatment of diabetic foot ulcers

• 作者: Caiqi Shen Wuhan Wei Aijun Zhang Changbo Tao Xueyang Li Yanping Guo Hanxiao Wei Qiang Li Peisheng Jin
• 来源期刊: 中国整形与重建外科（英文）
• 年，卷（期）: 2022,（1）
• 所属期刊栏目: Case Report
• 页码范围: 17-19
• 页数: 3页
• 语种: 中文

摘要

Diabetic foot ulcers are one of the most severe complications of diabetes that have imposed great financial and psychological burdens on diabetic patients. A Nocardia rubra cell wall skeleton (Nr-CWS) can be externally applied to accelerate wound healing. However, its clinical application has not yet been reported. Herein, we report two patients with diabetic foot ulcers treated with Nr-CWS. After wound debridement, the wound was covered with a sterile cotton ball infiltrated with an Nr-CWS that was diluted with 2.0 mL of saline. The covers were changed every two days until complete wound healing occurred. The two wounds healed after 3 and 12 weeks, respec-tively. This article aims to provide a new treatment for diabetic foot ulcers, with the hope that physicians may consider an Nr-CWS as a complementary method for the treatment of chronic wounds.