Synthesis,Crystal Structure and Fe3+Recognition of a Fluorescent Probe Based on Quinazolinone Derivative

• 作者: WANG Lin WANG Xiao-Feng XUE Meng-Wei DUAN Shu-Rong LI Ting YU Zhen-Zhen ZHANG Dun-Lin
• 来源期刊: 结构化学
• 年，卷（期）: 2022,（3）
• 页码范围: 55-61
• 页数: 7页
• 语种: 英文
• DOI: 10.14102/j.cnki.0254-5861.2011-3325

摘要

A novel quinazolinone derivative ethyl 2-(2-methyl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)ace-tate(EMOTA)was synthesized and characterized by HRMS,1H NMR,13C NMR spectroscopy and X-ray crystal-lography,and the ion recognition performance of the compound was studied by fluorescence analysis measure-ments.The results showed that probe EMOTA has a rapid fluorescence response,good selectivity and sensitivity to Fe3+.When the concentration of Fe3+was in the range of 0～10.0×10-5mol/L,the fluorescence quenching could be affected by the probe,and the detection limit was 1.65×10-6mol/L.In addition,the identification and detection of Fe3+in water samples were studied,and the results showed that probe EMOTA has high efficiency,significant sen-sitivity and high selectivity on the recognition and detection of Fe3+in water samples,which indicates probe EMOTA has a practical application prospect.