Rice is the staple food of more than half of the world's population,and major efforts are being made to improve rice yield.Rice yield is mainly determined by three components:number of panicles per plant,number of grains per panicle,and grain weight,which is positively associated with grain size.Therefore,grain size is an important agricultural trait for yield improvement in rice,and it is controlled by multiple genetic factors and environmental cues(Li et al.,2018).The final size of rice grains is largely determined by cell proliferation and cell expansion in the spikelet hull(husk),which sets the storage capacity of the grain and limits grain filling(Li et al.,2018).A number of quantitative trait loci for grain size have been identified and their underlying molecular functions unraveled.These include,for example,protein ubiquitination,chromatin modifications,transcription factors,RNA-mediated regulatory networks,and multiple plant hormones(Li and Li,2016).Among the plant hormones,brassinosteroids and cytokinin play pivotal roles in grain size control.Recently,Liu et al.(2021)reported the discovery of an unexpected novel link between the brassinosteroid and the cytokinin signaling pathways with a major impact on rice grain size.