Preparation of conductive and transparent dipeptide hydrogels for wearable biosensor

• 作者: Yafeng Jing Anhe Wang Jieling Li Qi Li Qingquan Han Xuefang Zheng Hongyu Cao Shuo Bai
• 来源期刊: 生物设计与制造（英文版）
• 年，卷（期）: 2022,（1）
• 所属期刊栏目: RESEARCH ARTICLES
• 页码范围: 153-162
• 页数: 10页
• 语种: 英文

摘要

Conductive and transparent dipeptide hydrogels are desirable building blocks to prepare soft electronic devices and wearable biosensors due to their excellent biocompatibility,multi-functionality,and physiochemical properties similar to those of body tissues.However,the preparation of such hydrogels featuring high conductivity and transparency is a huge challenge because of the hydrophobic feature of conductive additives making the doping process difficult.To overcome this issue,hydrophilic conductive polydopamine (PDA)-doped polypyrrole (PPy) nanoparticles are introduced into the dipeptide hydrogel networks to form conductive nanofibrils in situ to achieve a good level of hydrophilic templating of the hydrogel networks.This tech-nique creates a complete conductive network and allows visible light to pass through.The strategy proposed herein not only endows the dipeptide hydrogel with good conductivity and high transparency,but also provides a great potential application of conductive dipeptide hydrogels for body-adhered signal detection,as evidenced by the experimental data.