Research progress on the correlation between immunosuppressive population and SARS-CoV-2 variation

• 作者: Yu-Xia Zhou Cai-Hong Wang Xiao-Wen Yao Rong Wang Xiao-Hui Yu Jiu-Cong Zhang
• 来源期刊: 海南医科大学学报（英文版）
• 年，卷（期）: 2022,（5）
• 所属期刊栏目: Novel Coronavirus Column
• 页码范围: 1-4
• 页数: 4页
• 语种: 英文

摘要

Recently, some severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants represented by B.1.7 (Alpha), B.1.351 (Beta), P1 (Gamma), B.1.617 (Delta) and B.1.529 (Omicron) have higher transmission and pathogenicity. Especially, Omicron causes global panic because of its high mutation in infectivity and vaccine escape, and their emergence makes the epidemic more difficult to control. The latest research reports indicate that these new corona mutants may first be mutated in the special population of immunosuppressive patients, and long-term infection and artificial immunotherapy may promote the variation of SARS-CoV-2. Not only that, there are a large number of congenital or acquired immunosuppressive patients worldwide, and immunosuppressive patients infected with SARS-CoV-2 will also have different impacts on social public health security. Therefore, we should pay more attention to the immunosuppressive population. This paper will briefly analyze the correlation between immunosuppressive population and SARS-CoV-2 variation in the form of review.