Prediction of coating uniformity in batch fluidized-bed coating process

• 作者: Andrey A.Lipin Alexandr G.Lipin
• 来源期刊: 颗粒学报（英文版）
• 年，卷（期）: 2022,（2）
• 页码范围: 41-46
• 页数: 6页
• 语种: 英文

摘要

Coating of particulate materials in fluidized beds is a widely used technique to eliminate particle agglom-eration,provide slow release of an active substance,or protect active ingredients.When thin polymer shells are applied on a particle surface,it is important to determine the process parameters that provide coating uniformity.In this study,the degree of coverage,defined as the fraction of the coated surface of the particles,is proposed as a quantitative criterion of coating uniformity.A new model for the batch fluidized-bed coating process is presented.The model allows prediction of the function of particle dis-tribution according to the degree of coverage at a given process time and thereby enables assessment of coating uniformity.An algorithm for the numerical solution of model equations for a batch fluidized-bed coater is described.The influences of the main process parameters on the coating uniformity were shown.