第2页_药学学报(英文版)2021年出版文献-钛学术文献服务平台

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药学学报(英文版)

投稿

Acta Pharmaceutica Sinica B

CSTPCD

影响因子 1.2053

ISSN：

2211-3835

CN：

10-1171/R

出版周期：

双月刊

邮编：

100050

地址：

北京市先农坛街1号

出版文献量（篇）

688

总下载数（次）

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31. Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ERα to inhibit RANKL signaling

作者： Keqi Wang Yongyan Chen Shuo Gao Maosi Wang Mengmeng Ge Qian Yang Mingkai Liao Lin Xu Junjie Chen Zhiping Zeng Haifeng Chen Xiao-kun Zhang Ting Lin Hu Zhou

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 442-455

摘要： Although different types of drugs are available for postmenopausal osteoporosis,the limita-tion...
32. Organic carbon monoxide prodrug,BW-CO-111,in protection against chemically-induced gastric mucosal damage

作者： Dominik Bakalarz Marcin Surmiak Xiaoxiao Yang Dagmara Wójcik Edyta Korbut Zbigniew ?liwowski Grzegorz Ginter Grzegorz Buszewicz Tomasz Brzozowski Jakub Cieszkowski Urszula G?owacka Katarzyna Magierowska Zhixiang Pan Binghe Wang Marcin Magierowski

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 456-475

摘要： Metal-based carbon monoxide(CO)-releasing molecules have been shown to exert anti-inflammatory ...
33. Generated SecPen_NY-ESO-1_ubiquitin-pulsed dendritic cell cancer vaccine elicits stronger and specific T cell immune responses

作者： Yunkai Yang Xiaohan Guo Bo Hu Peng He Xiaowu Jiang Zuohuan Wang Huaxing Zhu Lina Hu Minghua Yu Meiqing Feng

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 476-487

摘要： Dendritic cell-based cancer vaccines(DC vaccines)have been proved efficient and safe in immunot...
34. Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma

作者： Xiaohua Liu Yu Zhang Yalei Li Juan Wang Huaqian Ding Wenjing Huang Chunyong Ding Hongchun Liu Wenfu Tan Ao Zhang

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 488-504

摘要： Medulloblastoma(MB)is a common yet highly heterogeneous childhood malignant brain tu-mor,howeve...
35. Layered dissolving microneedles as a need-based delivery system to simultaneously alleviate skin and joint lesions in psoriatic arthritis

作者： Kaiyue Yu Xiuming Yu Sisi Cao Yixuan Wang Yuanhao Zhai Fengdie Yang Xiaoyuan Yang Yi Lu Chuanbin Wu Yuehong Xu

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 505-519

摘要： Psoriatic arthritis(PsA)is a complicated psoriasis comorbidity with manifestations of psori-ati...
36. pH-sensitive and bubble-generating mesoporous silica-based nanoparticles for enhanced tumor combination therapy

作者： Zhiming Zhang Chenlu Huang Li Zhang Qing Guo Yu Qin Fan Fan Boxuan Li Bao Xiao Dunwan Zhu Linhua Zhang

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 520-533

摘要： Chemotherapy has been a major option in clinic treatment of malignant tumors.However,single che...
37. Cryptobiosis-inspired assembly of"AND"logic gate platform for potential tumor-specific drug delivery

作者： Hu Zhou Gang He Yanbin Sun Jingguo Wang Haitao Wu Ping Jin Zhengbao Zha

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 534-543

摘要： Developing tumor-specific drug delivery systems with minimized off-target cargo leakage re-main...
38. Cathepsin B-responsive and gadolinium-labeled branched glycopolymer-PTX conjugate-derived nanotheranostics for cancer treatment

作者： Hao Cai Yufan Xiang Yujun Zeng Zhiqian Li Xiuli Zheng Qiang Luo Hongyan Zhu Qiyong Gong Zhongwei Gu Yanhui Liu Hu Zhang Kui Luo

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 544-559

摘要： Multi-modal therapeutics are emerging for simultaneous diagnosis and treatment of cancer.Polyme...
39. Hypoxia-degradable and long-circulating zwitterionic phosphorylcholine-based nanogel for enhanced tumor drug delivery

作者： Shaojun Peng Boshu Ouyang Yongjie Xin Wei Zhao Shun Shen Meixiao Zhan Ligong Lu

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 560-571

摘要： Tumor microenvironment has been widely utilized for advanced drug delivery in recent years,amon...
40. Genome mining combined metabolic shunting and OSMAC strategy of an endophytic fungus leads to the production of diverse natural products

作者： Qian Wei Jian Bai Daojiang Yan Xiuqi Bao Wenting Li Bingyu Liu Dan Zhang Xiangbing Qi Dequan Yu Youcai Hu

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 572-587

摘要： Endophytic fungi are promising producers of bioactive small molecules.Bioinformatic anal-ysis o...
41. A four-protein metabolon assembled by a small peptide protein creates the pentacyclic carbonate ring of aldgamycins

作者： Qiaozhen Wang Xiaolong Tang Ping Dai Chuanxi Wang Weiyang Zhang Guodong Chen Kui Hong Dan Hu Hao Gao Xinsheng Yao

刊名：药学学报(英文版)

发表期刊： 2021年2期

页码: 588-597

摘要： Organic carbonates(OCs)are a class of compounds featured by a carbonyl flanked by two alkoxy/ar...
42. Targeting redox-altered plasticity to reactivate synaptic function:A novel therapeutic strategy for cognitive disorder

作者： Pei Wang Fang Wang Lan Ni Pengfei Wu Jianguo Chen

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 599-608

摘要： Redox-altered plasticity refers to redox-dependent reversible changes in synaptic plasticity vi...
43. Hedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment

作者： Jinghui Zhang Jiajun Fan Xian Zeng Mingming Nie Jingyun Luan Yichen Wang Dianwen Ju Kai Yin

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 609-620

摘要： The Hedgehog(HH)signaling pathway plays important roles in gastrointestinal carcinogen-esis and...
44. Natural products as LSD1 inhibitors for cancer therapy

作者： Yuan Fang Chao Yang Zhiqiang Yu Xiaochuan Li Qingchun Mu Guochao Liao Bin Yu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 621-631

摘要： Natural products generally fall into the biologically relevant chemical space and always posses...
45. Diversity of the reaction mechanisms of SAM-dependent enzymes

作者： Qiu Sun Mengyuan Huang Yuquan Wei

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 632-650

摘要： S-adenosylmethionine(SAM)is ubiquitous in living organisms and is of great significance in meta...
46. Can nanoparticles and nano-protein interactions bring a bright future for insulin delivery?

作者： Ting Zhang James Zhenggui Tang Xiaofan Fei Yanping Li Yi Song Zhiyong Qian Qiang Peng

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 651-667

摘要： Insulin therapy plays an essential role in the treatment of diabetes mellitus.However,frequent ...
47. S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling

作者： Pingping Luo Ming Zheng Rui Zhang Hong Zhang Yingxia Liu Wei Li Xiaoming Sun Qian Yu George L.Tipoe Jia Xiao

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 668-679

摘要： Alcoholic liver disease(ALD)causes insulin resistance,lipid metabolism dysfunction,and inflamma...
48. Isorhapontigenin protects against doxorubicin-induced cardiotoxicity via increasing YAP1 expression

作者： Panxia Wang Minghui Wang Yuehuai Hu Jianxing Chen Yanjun Cao Cui Liu Zhongkai Wu Juan Shen Jing Lu Peiqing Liu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 680-693

摘要： As an effective anticancer drug,the clinical limitation of doxorubicin(Dox)is the time-and dose...
49. Abrogation of USP7 is an alternative strategy to downregulate PD-L1 and sensitize gastric cancer cells to T cells killing

作者： Zhiru Wang Wenting Kang Ouwen Li Fengyu Qi Junwei Wang Yinghua You Pengxing He Zhenhe Suo Yichao Zheng Hong-Min Liu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 694-707

摘要： Targeting immune checkpoints such as programmed cell death protein 1(PD-1)and pro-grammed death...
50. A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

作者： Tailin He Jialin Shang Chenglong Gao Xin Guan Yingyi Chen Liwen Zhu Luyong Zhang Cunjin Zhang Jian Zhang Tao Pang

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 708-726

摘要： Ischemic stroke is the second leading cause of death worldwide with limited medications and neu...
51. Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation

作者： Yue Gao Shicheng Fan Hua Li Yiming Jiang Xinpeng Yao Shuguang Zhu Xiao Yang Ruimin Wang Jianing Tian Frank J.Gonzalez Min Huang Huichang Bi

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 727-737

摘要： The constitutive androstane receptor(CAR,NR3I1)belongs to nuclear receptor superfamily.It was r...
52. Ultra-short-course and intermittent TB47-containing oral regimens produce stable cure against Buruli ulcer in a murine model and prevent the emergence of resistance for Mycobacterium ulcerans

作者： Yamin Gao H.M.Adnan Hameed Yang Liu Lingmin Guo Cuiting Fang Xirong Tian Zhiyong Liu Shuai Wang Zhili Lu Md Mahmudul Islam Tianyu Zhang

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 738-749

摘要： Buruli ulcer(BU),caused by Mycobacterium ulcerans,is currently treated with rifampin-streptomyc...
53. A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors

作者： Yihui Song Min Zhao Yahong Wu Bin Yu Hong-Min Liu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 750-762

摘要： The protein tyrosine phosphatase Src homology phosphotyrosyl phosphatase 2(SHP2)is implicated i...
54. Functional metabolomics reveal the role of AHR/GPR35 mediated kynurenic acid gradient sensing in chemotherapy-induced intestinal damage

作者： Di Wang Danting Li Yuxin Zhang Jie Chen Ying Zhang Chuyao Liao Siyuan Qin Yuan Tian Zunjian Zhang Fengguo Xu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 763-780

摘要： Intestinal toxicity induced by chemotherapeutics has become an important reason for the interru...
55. Design,synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors

作者： Xiaowei Wu Mengdi Dai Rongrong Cui Yulan Wang Chunpu Li Xia Peng Jihui Zhao Bao Wang Yang Dai Dan Feng Tianbiao Yang Hualiang Jiang Meiyu Geng Jing Ai Mingyue Zheng Hong Liu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 781-794

摘要： Fibroblast growth factor receptors(FGFRs)have emerged as promising targets for anticancer thera...
56. Design,synthesis,molecular modeling,and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis

作者： Fanxun Zeng Shiliang Li Guantian Yang Yating Luo Tiantian Qi Yingfan Liang Tingyuan Yang Letian Zhang Rui Wang Lili Zhu Honglin Li Xiaoyong Xu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 795-809

摘要： Human dihydroorotate dehydrogenase(DHODH)is a viable target for the development of therapeutics...
57. Novel PF74-like small molecules targeting the HIV-1 capsid protein:Balance of potency and metabolic stability

作者： Lei Wang Mary C.Casey Sanjeev Kumar V.Vernekar Rajkumar Lalji Sahani Karen A.Kirby Haijuan Du Huanchun Zhang Philip R.Tedbury Jiashu Xie Stefan G.Sarafianos Zhengqiang Wang

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 810-822

摘要： Of all known small molecules targeting human immunodeficiency virus(HIV)capsid protein(CA),PF74...
58. A smart MnO2-doped graphene oxide nanosheet for enhanced chemo-photodynamic combinatorial therapy via simultaneous oxygenation and glutathione depletion

作者： Peng Liu Xin Xie Miao Liu Shuo Hu Jinsong Ding Wenhu Zhou

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 823-834

摘要： The combination of chemotherapy and photodynamic therapy provides a promising approach for enha...
59. An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis

作者： Xianyan Qin Yingying Xu Xu Zhou Tao Gong Zhi-Rong Zhang Yao Fu

刊名：药学学报(英文版)

发表期刊： 2021年3期

页码: 835-847

摘要： Localized delivery,comparing to systemic drug administration,offers a unique alternative to enh...
60. Editorial of Special Issue"The Biological Fate of Drug Nanocarriers"

作者： Wei Wu Tonglei Li Ying Zheng

刊名：药学学报(英文版)

发表期刊： 2021年4期

页码: 849-851

摘要： According to the Merriam-Webster dictionary,the word"fate"refers to"final outcome",among variou...

药学学报(英文版)基本信息

刊名	药学学报(英文版)	主编
曾用名
主办单位		主管单位
出版周期	双月刊	语种	eng
ISSN	2211-3835	CN	10-1171/R
邮编	100050	电子邮箱	yxxb@imm.ac.cn
电话	010-63026192	网址
地址	北京市先农坛街1号