DETERMINATION OF THERMODYNAMIC AND KINETIC PARAMETERS OF LARGE SCALE CHROMATOGRAPHIC SEPARATION OF SUGAR AND REDUCING SUGAR

• 作者: LiZhong ShuWenli 等
• 来源期刊: 中国反应性高分子：英文版
• 学科: 化学
• 关键词: 热力学性质 动力学参数 大型色谱分离 还原糖
• 年，卷（期）: 1996,（1）
• 页码范围: 84-91
• 页数: 8页
• 分类号: O629.1

摘要

The parameter identification model of large scale chromatography separation process is proposed.The phase equilibrium constants and lumped mass transfer coefficients of sugar and reducing sugar adsorption on D1,D2 and D3 resins as well as the axial dispersion coefficients of the fluid through packed columns are determined by means of the pulse-response experiment technique with an inert substance as a tracer and the chromatography measuring technique.The elution curve calculated from these parameters is good agreement with the experimental elution curve.The sensitivity analysis of these parameters is carried out ,and the result shows that the elution curves of chromatography separation are more sensitive to the variations of the phase equilibrium relationship than to the variation of the axial dispersion as well as the lumped mass transfer coefficients.