SESQUITERPENE GLUCOSIDES FROM ANTI-LEUKOTRIENE B4 RELEASE FRACTION OF TARAXACUM OFFICINALE

• 来源期刊: 亚洲天然物产研究（英文版）
• 学科: 生物学
• 关键词: Taraxacum officinale Compositae Anti-leukotriene B4 formation Germacrane Sesquiterpene
• 年，卷（期）: 2001,（3）
• 页码范围: 191-197
• 页数: 7页
• 分类号: Q94
• 语种: 英文

摘要

Chemical examination of the MeOH extract of the root of Taraxacum officinale, which exhibited inhibitory activity on the formation of leukotriene B4 from activated human neutrophils, has resulted in the isolation of 14-O-β-D-glucosyl-11,13-dihydro-taraxinic acid (1)and 14-O-β-D-glucosyl-taraxinic acid (2). The absolute stereostructure of 1 has been established by X-ray chrystallographic examination.