Synthesis and Antibacterial Activity of 3-( 5-Methylisoxazol-3-yl) - 1,2,4-triazolo [3,4- b ]-1,3,4-thiadiazine Derivatives
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摘要:
The condensed products 2—10 of 4-amino-5-mercapto-3-(5methylisoxazol-3-yl)-1,2,4-triazole (1) with chloroacetaldehyde, 2-bromocyclohexanone, chloranil, ω-bromo-ω-(1H-1,2,4-triazol-1-yl)acetophenone, 2-bromo-4'-substituted acetophenones and 2-bromo-6'-methoxy-2'-acetonaphthone were described. The antibacterial activities were also evaluated.