One-pot Synthesis of Isoxazolines Using Soluble Polymer-supported Acrylate

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2003,（1）
• 页码范围: 7-8
• 页数: 2页
• 语种: 英文

摘要

An effiacient liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described.Soluble polymer-supported acrylate reacted with nitrile oxides generated in-situ, followed by cleavage from the support giving corresponding isoxazolines in high yields and excellent purities.