Flow-Injection Electrochemiluminescence Detecting Rifampicin Based on Its Sensitizing Effect

• 来源期刊: 中国化学（英文版）
• 学科: 化学
• 年，卷（期）: 2004,（3）
• 页码范围: 279-282
• 页数: 4页
• 分类号: O6
• 语种: 英文

摘要

A new flow-injection electrogenerated chemiluminescence (ECL) method for the determination of rifampicin was developed. The method is based on the sensitizing effect of rifampicin on the weak ECL signal of electrochemical oxidation of luminol on the surface of the platinum flake electrode in the medium of 0.02 mol·L-1 Na2B4O7. This ECL response is in the range of 1.0×10-8-4.0×10-6 mol·L-1 rifampicin with a detection limit of 8.0×10-9 mol·L-1. The relative standard deviation is 1.8%. This method has been applied successfully to the determination of rifampicin in capsule, ocustilla and urine samples.