RNA interference： an exciting new target validation tool of drug action and therapeutic approach on cardiovascular diseases

• 作者: HeMing
• 来源期刊: 中国药理通讯
• 学科: 医学
• 关键词: RNA干涉 靶细胞 麻醉作用 RNAi 心血管疾病 抑制作用
• 年，卷（期）: 2005,（1）
• 页码范围: 48-50
• 页数: 3页
• 分类号: R54

摘要

RNA interference (RNAi) is an evolutionarily conserved mechanism for silencing gene expression by targeted degradation of mRNA. Short double-stranded RNAs, known as small interfering RNAs (siRNA), are incorporated into an RNA-induced silencing complex that directs degradation of RNA containing a homologous sequence.