Two-dimensional model of vesicle adhesion on curved substrates

• 来源期刊: 力学学报（英文版）
• 年，卷（期）: 2006,（6）
• 页码范围: 529-535
• 页数: 7页
• 语种: 英文

摘要

We develop a two dimensional model of a vesicle adhered on a curved substrate via long-range molecular interactions while subjected to a detachment force.The relationship between the force and displacement of the vesicle is investigated as a function of the substrate shape.It is shown that both the forcedisplacement relationship and the maximum force at pull-off are significantly dependent on the substrate shape.The results suggest that probes with different tip shapes may be designed for cell manipulation.For example,we demonstrate that a vesicle can be pulled off a flat surface using a probe with a curved tip.