Investigation on Voltammetric Behavior of Camptothecin and Its Analytical Application

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2006,（4）
• 页码范围: 551-556
• 页数: 6页
• 语种: 英文

摘要

The voltammetric behavior of camptothecin (CPT) in Britton-Robinson (B-R) buffer solutions (pH 2.09-9.07)was studied by the means of linear sweep voltammetry (LSV), cyclic voltammetry (CV) and normal pulse voltammetry (NPV) at a hanging mercury drop electrode. In different pH range of B-R buffer solutions, CPT could cause three reduction waves. In B-R buffer solutions (pH 2.09-5.46), wave P1 yielded by CPT was a two-electron wave.Between pH 6.01 and 9.07, CPT could yield two reduction waves P2 and P3. In addition, the pure CPT obtained from camptotheca acumina grown only in China was determined by NPV, and a linear response was observed in the tion limit for CPT.