Conjugate Additions of Secondary Amines and Water to Allenyl Perfluoroalkyl Sulfones

• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2006,（6）
• 页码范围: 775-780
• 页数: 6页
• 语种: 英文

摘要

Preparation of allenyl perfluoroalkyl sulfones from perfluoroalkyl sulfinyl chlorides and their reactions with secondary amines and water were studied. At room temperature secondary amines reacted readily with allenyl perfluoroalkyl sulfones to give the corresponding enamine adducts, which underwent rearrangement to afford conjugate enamines in refluxing toluene. Good diastereoslectivities were observed in the addition of diethylamine to γ-ethyl-γ-methylallenyl perfluoroalkyl sulfones. In refluxing acetonitrile, water could also undergo the similar addition with allenyl perfluoroalkyl sulfones.