The magic of four: induction of pluripotent stem cells from somatic cells by Oct4, Sox2, Myc and Klf4

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2007,（7）
• 页码范围: 578-580
• 页数: 3页
• 语种: 英文

摘要

The developmental process from a fertilized egg to a grown adult is programmed with remarkable accuracy. While the genetic information of the fertilized egg and its descendent somatic cells are the same, it is the selective expressions of the same genome that give rise to the 200 or so different cell types in an adult.