Stem cell self-renewal versus differentiation: Tumor suppressor Mei-P26 and miRNAs control the balance
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摘要:
Stem cells, which can self-renew and produce different cell types, have been shown to be regulated by extrinsic signals and intrinsic factors. Drosophila ovarian germline stem cells (GSCs), representing one of the well-studied stem cells, continuously proliferate and generate differentiated cystoblasts, which further develop into oocytes.