Effects of 17beta-estradiol on distribution of primordial germ cell migration in male chicks

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2008,（2）
• 页码范围: 243-248
• 页数: 6页
• 语种: 英文

摘要

Aim: To assess whether exogenous estradiol has any effect on migration of primordial germ cells (PGCs) in the chick. Methods: Fertilized eggs were treated with 17beta-estradiol (Ez) (80 lag/egg) at stage X (day 0 of incubation),stages 8-10 (incubation 30 h) and 13-15 (incubation 55 h). Controls received vehicle (emulsion) only. Changes in PGC number were measured on different days according to developmental stages. Results: In male right gonads,but not in female left gonads, at stages 28-30 (incubation 132 h) significant decreases in the mean number of PGCs aggregating were observed compared with the controls (P < 0.05) while the total PGC number in the fight and left gonads at each stage did not change (P > 0.05). Conclusion: The present study provides evidence that E2 has significant effects on the localization of PGCs in male fight, but not female left, gonads of chicken embryos at stages28-30, compared with controls.