Different evolutionary lineages of large and small heat shock proteins in eukaryotes

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2008,（10）
• 页码范围: 1074-1076
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/cr.2008.283

摘要

Dear Editor, Heat shock proteins (Hsps) occur in nearly all organisms [1],and usually act as molecular chaperones,promoting correct refolding and preventing aggregation of denatured proteins [2].Based on molecular weight,Hsps can be categorized into several families,including Hsp90,Hsp70,Hsp60,Hsp40 (so-called large Hsps) and small Hsps (sHsps,with the molecular weights varying from 12 to 43 kDa).