Preparation and characterization of 3-(triethoxysilyl) propyl isocyanate self-assembled monolayer on surface of chip

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2009,（5）
• 页码范围: 738-742
• 页数: 5页
• 语种: 英文
• DOI: 10.1007/s11434-009-0059-9

摘要

Monolayer of 3-(triethoxysilyl) propyl isocyanate was prepared on the slide by self-assembled tech-nique. X-ray photoelectron spectroscopy (XPS) was employed to analyze the elementary composition of the film. Contact angle of distilled water was measured to characterize the surface state. It was shown that 3-(triethoxysilyl) propyl isocyanate had been successfully assembled on the slide. The in-crease of contact angle to 80 demonstrated that the hydrophobicity of the surface of chip was in-creased significantly. Moreover, further self-assembly of bovine serum albumin (BSA) on 3-(trietho-xysilyl) propyl isocyanate was also carried out with the advantages such as simple and convenient preparation. Therefore, the potential of broader applications in the modification of micro-channel in the μ-TAS system, the immobilization of protein or peptide and the surface modification of materials are all expectative.