Highly efficient heterogeneous procedure for the conjugate addition of amines to electron deficient alkenes

• 来源期刊: 中国科学B辑(英文版)
• 年，卷（期）: 2009,（7）
• 页码范围: 874-878
• 页数: 5页
• 语种: 英文
• DOI: 10.1007/s11426-009-0075-2

摘要

The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes.K2CO3 supported on different carriers have been synthesized for the conjugate addition of amines and alkenes.After optimizing the reaction conditions,K2CO3/MgO was chosen as the most efficient catalyst for the reactions.The results showed that the catalyst was very efficient for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes.Operational simplicity,without need of any solvent,low cost of the catalyst used,high yields,reusability,excellent chemoselectivity,and applicability to large-scale reactions are the key features of this methodology.