Isolation, structural determination and cytotoxic activity of two new ceramides from the root of Isatis indigotica

• 来源期刊: 中国科学B辑（英文版）
• 年，卷（期）: 2009,（5）
• 页码范围: 621-625
• 页数: 5页
• 语种: 英文
• DOI: 10.1007/s11426-008-0146-9

摘要

Two new ceramides were Isolated from the 95% EtOH extract of traditional Chinese medicinal plant Isatis indigotica. Their structures were elucidated as 1-O-β-D-glucopyranosyl-(2S, 3R)-N-(2'-hydroxype-ntacosanoyl)-octadeca-11 E-sphingenine (1) and 1-O-β-D-glucopyranosyl-(2S,3R)-N-(2'-hydroxyhe xaco-sanoyl)-octadeca-11E-sphingenine (2) on the basis of spectroscopic data. Their cytotoxic effects were evaluated by using MTT method.