A G-coupled Receptor Protein Critical for Peripheral Nerve Myelination

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2010,（3）
• 页码范围: 105-106
• 页数: 2页
• 语种: 英文

摘要

Intercellular signaling between the axon and myelinating glial cells plays an essential role in the regulation of the myelination process. A recent study from Monk et al. has used a forward genetics approach in zebrafish to identify a G protein-coupled receptor that is necessary for Schwann cells to myelinate axons, thereby uncovering a critical component of the axo-glial signaling network.