Goldfish β-catenin cell-autonomously inhibits the expression of early neural development regulating gene vsx1

• 来源期刊: 科学通报(英文版)
• 学科: 生物学
• 关键词: 神经前体细胞 β-连环素 神经调节 基因表达 早期 转录因子基因 金鱼 胚胎发育过程
• 年，卷（期）: 2010,（2）
• 所属期刊栏目: ARTICLES
• 页码范围: 145-152
• 页数: 8页
• 分类号: Q421 Q26
• 语种: 英文

摘要

β-catenin gene is essential for the formation of normal dorsal axial structure in vertebrates. Recent studies have provided evidence that β-catenin has a certain role in restricting the amount of organizer-induced neurectoderm formation in zebrafish and Xenopus laevis. To further understand how β-catenin represses the induction of neurectoderm formation and whether the inhibition of neural progenitor fates is essential for the normal organizer formation, it was investigated whether β-catenin was involved in...