A New Avenue to Cure Cancer by Turning Adaptive Immune T Cells to Innate Immune NK Cells via Reprogramming

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2010,（5）
• 页码范围: 237-239
• 页数: 3页
• 语种: 中文
• DOI: 10.1093/jmcb/mjp016

摘要

Thymocytes after T-lineage commitment develop in the T-cell pathway. However, in a recent study, Li et al. (2010) demonstrated that inducing to delete Bcl11b gene in these thymocytes, even in mature T cells turns these cells into natural killer (NK) cells during the culture. They called this conversion 'reprogramming', and the reprogrammed killer cells 'ITNK cells'.