In vivo exploration of the functional activity of the non-coding 8q24 prostate cancer risk locus

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2010,（6）
• 页码范围: 787-789
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/aja.2010.102

摘要

Genome-wide association studies (GWAS) have successfully identified a substantial number of risk variants for prostate cancer [1-10]. In total, more than 20 single nucleotide polymorphisms (SNPs) that predispose to prostate malignancy have been found scat-tered throughout the genome in coding and non-coding regions.