Chiral N-formyl amino alcohol as Lewis basic organocatalyst for enantioselective hydrosilylation of ketimines

• 来源期刊: 科学通报(英文版)
• 学科: 化学
• 关键词: 对映选择性加成 氨基乙醇 刘易斯 手性 交通便利 发达国家 产量高 催化剂
• 年，卷（期）: 2010,（17）
• 所属期刊栏目: LETTERS
• 页码范围: 1726-1728
• 页数: 3页
• 分类号: O621.34 TQ254.15
• 语种: 英文

摘要

Easily accessible (1R,2S)-1,2-diphenyl-2-formamidoethanol has been developed as an effective Lewis base catalyst in the enantioselective hydrosilylation of ketimines, affording high isolated yields (up to 94%) and moderate to high enantioselectivities (up to 82%ee) for a broad range of ketimines.