The mystery is solved-CatSper is the principal calcium channel activated by progesterone in human spermatozoa

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（3）
• 页码范围: 351-352
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2011.9

摘要

Aremarkable advance in sperm physiology has recently been published in Nature.Two groups using patch clamping techniques on human sperm have solved a mystery about the sperm cell that has puzzled both andrologists and those involved in non-genomic cellular signalling for over 20 years.In these papers, Lishko1 and Strunker2 independently demonstrate that the universal characteristic effect of progesterone on sperm-a rapid influx of calcium-is via a sperm-specific channel CatSper.