Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles

• 作者: Bhumireddy Chinnachennaiahgari Venkatesh Konda Mahesh Thunga Radha Lakshmi Venkatapuram Padmavathi
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: 1-Aroyl-2-Styrylsulfonylethene 1 3-Dipolar CYCLOADDITION CHLORAMINE-T ANTIMICROBIAL Activity
• 年，卷（期）: yjhxgjqkyw_2011,（3）
• 页码范围: 78-86
• 页数: 9页
• 分类号: O6

摘要

A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity.