A new Speedy/RINGO protein may help regulate male meiosis

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（3）
• 页码范围: 363
• 页数: 1页
• 语种: 英文
• DOI: 10.1038/aja.2011.30

摘要

Reproductive biology, although seen as a specialty study area, has many unique biology models that offer insight into the regulation of cellular processes that are shared by many different cell types.The most celebrated example of this was the discovery of the cyclins and their role in cell cycle regulation in Xenopus oocytes.1-4 Meiosis is one such aspect of this field that presents an important window for the study of both cell cycle regulation and chromatin structure.Meiosis only occurs in the testis and ovaries, and only in the germ cells that eventually produce sper-matogonia and oocytes.5 In this issue, Cheng and colleagues6 present data to suggest that a novel protein they originally identified in the rat testis, called LM23, is crucial for the regulation of meiosis in spermatogenesis.It is perhaps fitting that LM23 is a member of a family of proteins called Speedy/RINGO that regulate cyclins.7