Selective cell death mediated by small conditional RNAs:a novel therapeutic approach to cancer therapy

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（2）
• 页码范围: 181-182
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2010.148

摘要

Targeted molecular therapy has been an elusive goal in the treatment of neo-plastic diseases.While chemotherapy has improved the outcome of many cancers, a non-selective cytotoxic approach invariably causes damage to normal cells, resulting in side effects and limiting treatment efficacy.This is evident in the evolution of treatment for castration-resistant prostate cancer (CRPC).