Regulating cell differentiation at different layers

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2011,（6）
• 页码范围: 319
• 页数: 1页
• 语种: 英文
• DOI: 10.1093/jmcb/mjr036

摘要

Cell differentiation is a basic behavior in the developmental process of multi-cellular organisms,through which various cell types are generated from one embryonic cell for further building different tissues and organs of animals or plants.It is estimated that there are more than two hundred cell types in a human body.To understand the molecular mechanisms of cell differentiation,researchers usually focus on a question how particular genes are selectively expressed during the differentiation process.However,more and more evidence indicates that the regulation of cell differentiation is far beyond simply controlling the expression of genetic program,which is supported by the collection of four research articles in this issue that the regulation of cell differentiation involves various factors at different layers,including epigenetics,metabolism and cell-cell interaction.