Setting a highway for converting skin into neurons

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2011,（6）
• 页码范围: 322-323
• 页数: 2页
• 语种: 英文
• DOI: 10.1093/jmcb/mjr029

摘要

Direct conversion of human skin fibroblasts into induced neuronal (iN) cells has been recently achieved by using different combinations of transcription factors eventually associated with microRNAs.These findings lay the ground for a straightforward and efficient generation of human neurons in vitro with elaborated functional properties instrumental for disease modeling and cell-based approaches of brain repair.