Reconstituting mammalian spermatogenesis using stem cells

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（6）
• 页码范围: 795-796
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2011.135

摘要

While stock markets and economies are smoldering all over the world,stem cell science is on fire.The promise of curing many untreatable forms of human male infertility is now one small step closer based on a recent paper in Cell.1 In this work,scientists from Kyoto University in Japan created mature,fertile sperm from embryonic and induced pluripotent stem cells by grabbing the primitive germ cells called primordial germ cells just as they were being made from their pluripotent precursors in vitro and transplanting them back into genetically sterile mice.