α2 integrin as regulator of metastatic potential

• 来源期刊: 中国药理学报（英文版）
• 年，卷（期）: 2011,（3）
• 页码范围: 279
• 页数: 1页
• 语种: 英文
• DOI: 10.1038/aps.2011.12

摘要

Regulation of cellular events is a complex process that involves several factors in their specific interactions and interplays.However, this complexity signs also exist specificity and changes in single protein, and could significantly influence the properties and responses of cells. Recently, Ramirez and colleagues[1]provided innovative results that emphasize the important and selective role of one specific protein, α2 integrin, in the complex process of tumor metastasis.This protein, as a part of heterodimeric 2β1 integrin, was identified as a metastasis suppressor in both breast and prostate cancer.