A good molecular target for prostate cancer chemotherapy

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（2）
• 页码范围: 207
• 页数: 1页
• 语种: 英文
• DOI: 10.1038/aja.2010.172

摘要

An exciting new basic medical research study shows that inhibition of the activity of the kinesin spindle protein Eg5 effectively blocks cell division and induces cell death in prostate cancer cells.1 The potent anticancer drug S-(methoxytrityl)-L-cysteine(S(MeO)TLC)spe-cifically blocks activity of Eg5 in prostate cancer cells, arrests cell division, induces cell death during mitosis and inhibits prostate cancer cells in a mouse model of prostate cancer.