Actin regulation during abscission: unexpected roles of Rab35 and endocytic transport
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摘要:
The final abscission event of cytokinesis is a complex cellular event that results in the separation of daughter cells and the completion of cell division.Multiple studies during the last decade have identified numerous proteins that have been shown to be required for the abscission,although the mechanisms and regulation of the abscission event are only beginning to emerge.It has become clear that the actin cytoskeleton plays a pivotal role in the initiation and completion of cytokinesis (reviewed in [1]).