Polymorphisms in microRNA targets: a source of new molecular markers for male reproduction

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（3）
• 页码范围: 505-508
• 页数: 4页
• 语种: 英文
• DOI: 10.1038/aja.2011.4

摘要

Dear Editor, Herein we discuss the impact of microRNA (miRNA) target genetic variability in male infertility genes, which can represent a source of novel molecular-genetic markers that can be used for the diagnosis of male infertility.Male-factor infertility accounts for 30%-40% of infertility cases.The causes of spermatogenetic failure found in most cases of non-obstructive azoospermia or severe oligozoospermia still remain idiopathic.1