Investigating the bona fide differentiation capacity of human pluripotent stem cells

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2012,（1）
• 页码范围: 6-8
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/cr.2011.142

摘要

Human pluripotent stem cells (hPSCs) have been perennially paraded as a source of cells for cell replacement therapies because they can (theoretically) give rise to any single cell type within the human body [1].Hence,they can create in vitro a vast number of any human cell type to replace the diseased cell population that a patient might require — this is a salient goal that regenerative medicine aspires to deliver on [2].However,despite the ever-expanding menagerie of therapeutically relevant differentiated lineages being created from hPSCs,usage of these stem cell-derived progeny for regenerative medicine still remains an uncertainty.