Portal vein thrombosis following percutaneous transhepatic cholangiography-An unusual presentation of Prothrombin (Factor Ⅱ) gene mutation

• 作者: Ian M Brennan Muneeb Ahmed
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Percutaneous TRANSHEPATIC CHOLANGIOGRAPHY Portal vein THROMBOSIS PROTHROMBIN gene mutation HEREDITARY THROMBOPHILIA
• 年，卷（期）: 2012,（5）
• 页码范围: 224-227
• 页数: 4页
• 分类号: R575

摘要

Portal vein thrombosis is an uncommonly reported complication of percutaneous transhepatic cholangiography (PTC). A thorough review of the available literature shows no reported cases. In this case, a 29 year old female presented on two separate occasions with portal vein thrombosis following PTC without drain placement. This unusual complication of image guided percutaneous biliary access is unreported in the literature and prompted evaluation of the patient’s coagulation parameters. A thrombophilia screen demonstrated a mutation in the Prothrombin (Factor Ⅱ) gene. A thorough literature review shows no reported cases of portal vein thrombosis following percutaneous biliary access, is an unusual complication, and should raise suspicion of an underlying pro-coagulant state.