Two-step generation of induced pluripotent stem cells from mouse fibroblasts using Id3 and Oct4

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2012,（1）
• 页码范围: 59-62
• 页数: 4页
• 语种: 英文
• DOI: 10.1093/jmcb/mjr038

摘要

Dear Editor,Somatic cells can be reprogrammed into pluripotent stem cells,called induced pluripotent stem cells (iPSCs),by defined transcription factors (Takahashi et al.,2006).The reprogramming of somatic cells may be a continuous stochastic process in which nearly all somatic donor cells have the ability to give rise to iPSCs with continuous passaging and the expression of defined factors (Hanna et al.,2009).