Mapping enhancer and promoter interactions

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2012,（5）
• 页码范围: 789-790
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/cr.2012.49

摘要

Histone modifications have previously been leveraged to map the locations of candidate enhancer and promoters in one dimensional genomic space.Chepelev et al.report the first Chromatin Interaction Analysis with Paired-End Tag (ChlA-PET) sequencing of a specific histone modification to systematically map long-range physical interactions among enhancer and promoters,yielding insights into the nature of these interactions.