Telomerase turns telomere dysfunction from bad to worse

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2012,（5）
• 页码范围: 665-666
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2012.37

摘要

Telomere integrity is critical for proliferation and survival of cells.Telomere dysfunction,often resulting from telomere attrition,causes genomic instability leading to cell death or malignant transformation.Telomerase is essential for maintaining telomere length and to immortalize cancer cells.